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KMID : 0191119930080060458
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Journal of Korean Medical Science
1993 Volume.8 No. 6 p.458 ~ p.463
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Thymic carcinoid tumor combined with thymoma - neuroendocrine differentiation in thymoma? -
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Cho Kyung-Ja
Ha Chang-Won
Koh Jae-Soo
Zo Jae-Il
Jang Ja-June
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Abstract
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carcinoid tumor of the thymus combined with thymoma in a 62-year-old man is described. The mediastinal tumor had been present for 13 years and was associated with pure red cell aplasia. Carcinoid tumor occupied the central two-thirds of the tumor, consisting of nests and trabeculae of monotonous round cells, which ultrastructurally showed many intracytoplasmic dense-core granules. Typical spindle cell type thymoma surrounded the carcinoid area. Clinico-pathologic findings of this unique case suggested that the carcinoid tumor developed within a preexisting thymoma, illustrating a possibility of neuroendocrine differentiation of thymic epithelial cells.
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KEYWORD
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thymus, carcinoid tumor, neuroendocrine carcinoma, thymoma
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